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Information gathered from cell-free systems, cell cultures, animal models, and human studies, together will provide important insights to our understanding of hormonal cancer causation, development, and prevention; the primary objective of these Symposia. A special emphasis will continue to be placed on the two major endocrine-related cancers, that is, breast and prostate. Other highly relevant cancers to be addressed are ovarian and endometrial. Emerging fields that will be examined are colon, lung, and pancreatic cancers in relation to hormones.