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This issue of Veterinary Clinics: Small Animal Practice, guest edited by Drs. Gregory R. Lisciandro and Jennifer M. Gambino, will cover Diagnostic Imaging: Point-of-care Ultrasound. This is one of six issues each year. Articles in this issue include, but are not limited to: Lung Ultrasound Fundamentals, "Wet versus Dry" Lung, Signs of Consolidation; Lung Ultrasound for Pulmonary Contusions; Lung Ultrasound for Pneumothorax; Ultrasound of the Diaphragm; Focused Cardiac Ultrasound in the Cat; Focused Cardiac Ultrasound in the Dog; TFAST Accurate Diagnosis of Pleural and Pericardial Effusion, Caudal Vena Cava; AFAST Target-organ Approach and Fluid Scoring System; Ultrasound of the Emergency Renal Patient; Hallmark Sonographic Signs of Ileus, Pneumoperitoneum and Right Upper Quadrant Disease; Thromboembolic Disease; Musculoskeletal; Ocular Abnormalities and Optic Nerve Sheath Diameter; and Global FAST for Patient Monitoring and Staging