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Total Synthesis of Leucascandrolide A

Lingua IngleseInglese
Libro In brossura
Libro Total Synthesis of Leucascandrolide A Lori J. Van Orden
Codice Libristo: 06813011
Casa editrice VDM Verlag Dr. Mueller E.K., settembre 2008
The total synthesis of Leucascandrolide A has been §of interest to many chemists for the twelve year... Descrizione completa
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The total synthesis of Leucascandrolide A has been §of interest to many chemists for the twelve years §that have passed since it was first isolated. §Leucascandrolide A''s potent biological activity §towards both yeast and cancer cell lines no doubt §make it an interesting synthetic target, but §synthetic chemists are most attracted by its §distinct structural features including a 14-membered §macrolide ring, two tri-substituted tetrahydropyran §moieties, and eight stereocenters. Although the §bulk of this book is dedicated to the methodology of §the Mukaiyama aldol-Prins reaction and its §application towards this total synthesis, there is a §short chapter included at the end which details §studies conducted towards a reagent-controlled, §diastereoselective synthesis of 2,5-disubstituted §tetrahydropyran rings.

Informazioni sul libro

Titolo completo Total Synthesis of Leucascandrolide A
Lingua Inglese
Rilegatura Libro - In brossura
Data di pubblicazione 2008
Numero di pagine 124
EAN 9783639033212
ISBN 3639033213
Codice Libristo 06813011
Peso 192
Dimensioni 229 x 154 x 11
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